Siren Raises $11.8 Million to Power Commercial Expansion of its Smart Fabric Remote Patient Monitoring Solution

May 27, 2020

Siren, a medical device company that has developed breakthrough technology to embed microsensors within fabric, allowing for mass production of affordable, washable smart textiles with remote patient monitoring applications, announced today that it has raised $11.8 million in funding led by Anathem Ventures, with participation from existing investors DCM, Khosla Ventures, 500 Startups, and Peter Thiel’s Founders Fund. In connection with this Series B round of funding, DCM Partner Jason Krikorian will join Siren’s board and Anathem Managing Partner Crystal McKellar will join Siren as an advisor.

 

Since its founding in 2015, Siren has raised $22 million across three funding rounds to position itself for commercial expansion, including a previously undisclosed $6.5 million Series A in 2018 and a $3.4 million seed round. Siren was the TechCrunch CES 2017 Hardware Battlefield Winner, and was named 2018 CES Best of Innovation for its innovative smart textile technology. 

 

Empowering Doctors to Effectively Care for Patients Remotely

 

Siren’s first commercial product is an FDA-registered temperature monitoring sock that connects wirelessly to a software application, allowing podiatrists to detect early signs of inflammation in patients at risk of developing diabetic foot ulcers. The onset of diabetic foot ulcers represents a dangerous condition that, when left unchecked, can lead to serious complications, including amputation. Today, podiatrists largely rely on in-clinic visits to manually monitor the temperature elevations that are the precursor to a diabetic foot ulcer. However, ulcers form in a matter of hours or days and can worsen rapidly between such visits. Siren’s solution enables real-time detection and early intervention, which can prevent the serious complications that result in over 100,000 lower limb amputations every year and cost the US healthcare system over $43 billion annually. 

 

COVID-19 Changing Healthcare Now and Forever

 

Siren’s remote monitoring solution is particularly valuable during the COVID-19 pandemic, as it allows healthcare practitioners to stay engaged with and care for their patients remotely, limiting in-clinic visits to true emergencies while delivering additional services for physician practices through CMS’ recent expansion of Medicare reimbursement for remote patient monitoring services. 

 

“COVID-19 has changed healthcare now and forever. Digitization and virtual care is no longer a nice-to-have, it’s a need-to-have. Patients need remote patient monitoring to collect and send crucial health data to their physicians. Clinics, by transitioning some medical staff into virtual monitoring, can stay operational, prevent job loss, and allow patients continued access to care,” commented Ran Ma, CEO of Siren. “Additionally, as a medical device company, we have changed the way that we do business - how we make sales, provide customer support, and how our products work. The companies who not only survive, but thrive, are the ones best able to evolve and help their customers adapt to this new world.”

 

Series B lead and Anathem Ventures Managing Partner Crystal McKellar said, “Technology, at its best, should deliver higher functionality at a fraction of the cost. In the healthcare space, this means improving patient outcomes while reducing the financial burden to the system. Siren’s breakthrough technology combines all of these important adoption drivers, and I am thrilled to partner with Siren to help further the company’s growth.” 

 

DCM Partner Jason Krikorian, a long-time Siren investor who co-led Siren’s 2016 seed round, noted, “When we initially invested, what I saw was a resourceful team and a creative and elegant product that would represent an enormous improvement for patient care and cost-effective physician workflows in any environment.  The current pandemic has made it clear that remote monitoring solutions will be a critical part of any physician’s practice.  I’m excited to work even closer with the team on this next phase of growth.”

 

About Siren

 

Siren is a technology company founded in 2015 by Ran Ma, Henk Jan Scholten, and Jie Fu that has developed proprietary technology to embed microsensors into fabric, allowing for the mass production of affordable, washable smart textiles. Siren’s products seamlessly integrate into their users’ everyday lives while providing real-time biofeedback to patients and their doctors. Siren’s first commercial product is an FDA-registered temperature monitoring sock for the early detection of inflammation that leads to diabetic foot ulcers, which costs the health system over $43 billion a year and leads to over 100,000 lower limb amputations annually in the United States. www.siren.care

 

About DCM 

 

DCM is a venture capital firm with over $4 billion under management. Since 1996, DCM has invested in more than 400 technology companies across the U.S. and Asia. With offices in Silicon Valley, Beijing, and Tokyo, DCM empowers its entrepreneurs with hands-on operational guidance and a global network of business and financial resources. www.dcm.com

 

About Anathem Ventures 

 

Anathem Ventures is an early stage venture capital fund that invests in the Seed to Series B rounds of great companies that have developed breakthrough technology with strong IP protection that they are leveraging to win and own well-defined, high-margin markets. Anathem is located in Jackson Square in the heart of San Francisco. www.anathemventures.com

 

Media Contact

 

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Siren Appoints Chief Commercial Officer to Lead National Expansion

May 18, 2020

Siren, a medical device company that has developed breakthrough technology to embed microsensors within fabric, allowing for mass production of affordable, washable smart textiles with remote patient monitoring applications, announced today the appointment of David Castiglioni as Chief Commercial Officer. Mr. Castiglioni brings an extensive background of startup commercial experience to the Siren leadership team from both the medical device and biotechnology industries and will report to Ran Ma, CEO and co-founder. In his role, Mr. Castiglioni will oversee all aspects of commercialization of Siren’s first product, an FDA-registered temperature monitoring sock that connects wirelessly to a software application, allowing healthcare practitioners to detect early signs of inflammation in patients at risk of developing diabetic foot ulcers. His responsibilities will include leading and driving sales, go-to-market planning, strategic partnerships, clinical education, and customer success. 

 

Mr. Castiglioni has led the commercialization of numerous new and innovative medical device platforms. He has over 20 years of medical device sales and marketing experience, including senior executive positions at Abbott Vascular and Intuitive Surgical. During his 7 years at Intuitive Surgical, he served in numerous leadership roles of increasing responsibility as part of the team that drove early-stage adoption of the daVinci robotic surgery system across the globe. Most recently, he was the Vice President of Sales at VitalConnect, leading commercial expansion of the company’s Vista Solution remote patient monitoring platform in North America. 

 

Mr. Castiglioni commented, “I am extremely excited to join the leadership team at Siren and bring a transformational technology to market that will help patients suffering from severe chronic disease. Throughout my career, I have been driven by my passion to improve patient care and commercializing technologies that address unmet clinical needs. Siren’s remote patient monitoring platform aligns with my commitment to putting patients first and represents an enormous improvement for patient care, particularly for those at risk of developing severely debilitating complications of diabetes and associated neuropathy.”

 

“We are delighted to welcome David to the team as our Chief Commercial Officer during this exciting period in Siren’s national expansion,” said Ran Ma, CEO and founder at Siren. “His passion and commitment for putting patients first, combined with his ability to strategically build strong customer relationships, brings a valuable skill set to the company’s leadership team. David’s extensive healthcare, technology, and medical device experience and track-record means that Siren will be well positioned for our growth phase.”

 

About Siren

Siren is a technology company founded in 2015 by Ran Ma, Henk Jan Scholten, and Jie Fu that has developed proprietary technology to embed microsensors into fabric, allowing for the mass production of affordable, washable smart textiles. Siren’s products seamlessly integrate into their users’ everyday lives while providing real-time biofeedback to patients and their doctors. Siren’s first commercial product is an FDA-registered temperature monitoring sock for the early detection of inflammation that leads to diabetic foot ulcers, which costs the health system over $43 billion a year and leads to over 100,000 lower limb amputations annually in the United States. https://siren.care

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Dr. Rimi Statkus Explains Tech Behind Siren Socks

May 13, 2020

Northern Illinois Foot and Ankle Specialists are offering cutting edge technology and care delivered by a top notch team to distinguish themselves in the field of podiatry. We are thrilled to have them integrate Siren in to their practice. Watch as Dr. Statkus explains how Remote Patient Monitoring technology and the Siren Sock System is keeping high risk patients monitored from the safety of their own home.

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Where Telehealth Stops and Remote Patient Monitoring Starts

May 12, 2020

REMOTE PATIENT MONITORING vs Telehealth: Which is right for you?

COVID-19 has brought to light for patients and providers the importance of Remote Patient Monitoring and Telehealth. While they are often lumped in one large “Telemedicine” category and are both valuable in their own ways, these two modalities are in fact different.

What is Remote Patient Monitoring?

Remote Patient Monitoring (often abbreviated as RPM) is a method of healthcare delivery that uses the latest advances in IT to gather patient data outside of traditional healthcare settings. It’s about using technologies to bridge the gap between traditional physical settings of your clinic and people living their every day lives. The most effective RPM systems often consist of consumer-friendly, wearable tech products that seamlessly integrate in to the users life, and a platform for clinics to streamline the data collected and provide a clear picture of the patients health. RPM is giving clinicians the power to know what’s actually occurring with their patients on a daily basis, as it happens, vs relying on their routine scheduled check in, or even a check in via telehealth. Patients are provided with a steady stream of biometric data to the healthcare professionals monitoring their treatment. It automates the process to an extent that makes it easier for both individual and provider to keep on top of the situations in real-time.

What is Telehealth?

Telehealth was originally created as a way to treat patients who were located in remote places, far away from local health facilities or in areas with shortages of medical professionals. While it is still used today to address these problems, it is increasingly becoming a tool for convenient basic medical care.  In short, telehealth is the practice of medicine using electronic and telecommunications technologies (think zoom, facetime, skype, etc.) and services to provide care from a distance. Today’s connected patient wants to waste less time in the waiting room at the doctors, and get immediate care for minor conditions when they need it. Telehealth can be used as a tool, but maybe not a solution for high risk patients. It should be used to screen patients, triage patients, and care for patients who do not need medical intervention.

 

As we know, COVID-19 can be harmful and even fatal for people with compromised health, and both Remote Patient Monitoring and Telehealth can help these patients avoid exposure. While telehealth can provide routine care for patients with chronic disease who are at high risk, it is limited in proactively alerting the patient or physician of potential ailments as remote patient monitoring can do.

 

Siren has the best in class Remote Patient Monitoring solution to continuously track foot temperature, keeping patients and providers connected by helping track issues related to inflammation or injury. Temperature monitoring, in contrast to visual checks alone, has been shown to improve outcomes related to ulcers by 87%.*

 

Contact us to learn more about our Siren Smart Sock system.

 

For more information on RPM and Podiatry, click here.

*https://siren.care/research/

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Remote patient monitoring and podiatry during COVID-19

April 16, 2020

People with neuropathy and those at risk for diabetic foot ulcers are particularly vulnerable during COVID-19. They need high-quality care to avoid complications. But many are scared to see their doctor, and don't know how to keep in touch with their podiatrist from home. In turn, podiatrists are seeing a decline of patients coming in for in-person visits. Remote patient monitoring offers a critical solution to deliver the best care for the patients that need it the most.

Impact of COVID-19 on diabetic foot care

People at risk for foot ulcers are also the most vulnerable when it comes to COVID-19. Many are older, have diabetes, and other co-morbidities that make the Corona-virus particularly dangerous for them. But especially now they need the care to make sure they don't develop foot complications. In order to keep people at home and out of the hospital, it's crucial for their health that they remain connected with their podiatrist.

  1. Less in-person visits and increased risk of complications. Patients are scared to come into the office and are cancelling appointments unless absolutely necessary. The fear is easily justified, but by not going in for regular in-person visits and seeing their doctors as often, they have an increased risk of developing diabetic foot ulcers. Diabetic foot ulcers can be fatal and have extreme consequences. Using remote patient monitoring, patients can be safely monitored from the comfort of their home without having to come into the office.
  2. Risk for healthcare providers. Due to exposure and infection rate, the number of staff available to see patients can decrease. As the virus continues to spread, health care providers will be forced to quarantine themselves. As a result, remaining providers will have to work more with less resources.
  3. Reduced access to care. The cancellations of these appointments are costly to the clinics as revenues are reduced. Medical assistants and nurses may have to be furloughed. Especially smaller and rural clinics are at risk, even though these are crucial for their communities. If clinics start closing, it reduces access to care for our most vulnerable patients. Siren allows clinics to keep their healthcare workers safe, because they can transition into remote patient monitoring instead of being furloughed.

How can Remote Patient Monitoring help your practice during COVID-19?

  1. Maintain relationships with high risk patients. Stay engaged and treat your patients even if they are unable to come in to the office. This will make your patients feel safe, knowing they are still being monitored and cared for by their physician. You can manage and limit in-person visits to only those which are absolutely necessary, while also creating better care for patients at home.
  2. Continue to monitor patients and avoid severe diabetic foot complications. Many patients with neuropathy are at high-risk to develop life-threatening wounds. Without close monitoring and regular check-ins, wounds can go unnoticed. RPM provides the means for monitoring patients who are at greatest risk during their period of self-isolation, protecting clinic staff and patients alike.
  3. Keep your clinic open and retain talented staff. RPM provides a provides a means to supplement some of the lost income from appointment cancellations for routine visits. The reimbursement is carved out specifically for the technology component of remote patient monitoring, so these programs can be more profitable than traditional telehealth services (CPT 99453, 99454, 99457 and 99458). You can keep your office open and retain talented and loyal staff.

Remote temperature monitoring for diabetic foot care during COVID-19

COVID-19 is here and it’s probably going to get worse before it gets better, but we are confident we will get through this difficult time together and that we can still save limbs and lives. With remote temperature monitoring, you can keep patients healthy and at home, and retain your staff to deliver the highest quality of care.

Contact us at [email protected] to discuss how we can help your patients and your practice to get going quickly.

Resources

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Neuropathy-Linked-to-Back-Pain

Is Diabetic Neuropathy Linked to Back Pain?

January 30, 2019

If you have diabetic neuropathy and experience back pain, you might wonder if the two are linked.

In fact, it's possible the two symptoms have common causes. While back pain can point to a number of different conditions, neuropathy could be one of them.

Neuropathy is caused by damage to your nerves. Since your spine is a major center of the nervous system, spinal nerve damage might be a cause for your back pain.

So, what causes nerve damage? Actually, there are more than 100 potential causes of neuropathy, diabetes being just one of them. Other causes include autoimmune disease, substance abuse, and injury.

Click here for more information about the relationship between neuropathy and back pain.

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If you're interested in reading more, check out Diabetes Health: Why Do My Feet Feel Numb?

 

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diabetic-foot-pain

The 411 on Diabetic Foot Pain

October 3, 2017

Pain in your feet is one of the first signs or symptoms that you may be experiencing a complication of diabetes. You've probably heard of many common foot problems like corns and bunions. But, have you heard of neuropathy? This type of nerve damage may be the reason behind your foot pain.

Today, we're going to go over the basics of why your feet may hurt, and talk about some treatment options and solutions.

Why do my feet hurt?

One of the reasons your feet may hurt is because of neuropathy. Neuropathy is a type of nerve damage that may cause feelings of pain or numbness in your feet.

It is a common problem, with up to 80% of people with diabetes having the disease. It happens for a number of reasons including blood sugar levels, genetics, and lifestyle.

 

How can I find out the cause of my foot pain?

The best thing you can do is talk to your primary care doctor or see a podiatrist with experience in diabetic foot pain.

Your doctor may conduct a series of tests to see whether or not you have neuropathy. There may be other reasons for your pain, so it's important to tell your doctor any symptoms you are having.

What can I do about foot pain?

There are a number of things you can do for your foot pain. Before trying something, talk with your doctor. Some things you can do include:

  • Keep your blood glucose levels under control
  • Manage your health with your care team
  • Discuss pain medications both over-the-counter and prescription
  • Try acupuncture to relieve pain
  • Use a TENS unit
  • Try pain cream or gel
  • Use lidocaine
  • Try capsaicin ointments or salves

The best thing you can do is treat your pain and prevent the problem from getting worse. Talk to your doctor about your risks for neuropathy and other foot problems that may cause pain

Is neuropathy a serious problem?

The important thing to know is that while neuropathy can cause pain, it can also lessen your ability to feel pain. Typically, painful neuropathy usually happens first and then this leads to leads to painless neuropathy. So over time, you may be unable to feel pain, heat or cold in your feet.

Both cases are very dangerous because your pain signals are off. Because of this, you might miss an injury, and these small injuries can become infected, gangrene and turn into an ulcer.

Neuropathy is one of the main causes of diabetic foot ulcers. So, it's important to find out if you have it so you can take steps to prevent further problems.

More information on foot pain and nerve damage:

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